叶剑雄，男，1984年7月出生，福建泉州人，现为福建师范大学数统学院副教授，硕士生导师，数学系主任，福建省生物数学学会常务理事，福建省运筹学学会理事。
研究方向：数学建模与应用、系统优化与控制、计算系统生物学等
联系方式：jxye@fjnu.edu.cn
教育经历：
2008/09-2011/10，大连理工大学，数学科学学院，博士
2006/09-2008/06，大连理工大学，数学科学学院，硕士
2002/09-2006/06，福建师范大学，数学与计算机科学学院，学士
科研与学术工作经历：
2021/6-至今，福建师范大学，数学与统计学院，副教授
2016/1-2021/6，福建师范大学，数学与信息学院，副教授
2018/8-2019/8，澳大利亚Curtin University，访问学者
2013/07-2015/09，华中科技大学，能源与动力工程学院，博士后
2011/12-2015/12，福建师范大学，数学与计算机科学学院，讲师
主持或参加科研项目（课题）及人才计划项目情况：
1. 国家自然科学基金青年项目，11301081，不完全信息代谢网络广义和混杂系统建模及优化控制，2014/01-2016/12，主持，已结题
2. 中国博士后科学基金面上项目, 2014M552027，一类不确定参数变界扰动的混杂系统鲁棒最优控制研究, 2014/04-2015/06，主持，已结题
3. 国家自然科学基金面上项目，11671335，具有混合约束的非光滑双层最优控制理论与算法，2017/01-2021/12，项目组成员（排名第二），已结题
4. 福建省自然科学基金面上项目，2021J01660，基于极小极大最优控制的动态代谢通量计算模型与优化，2021/11-2024/11，主持
5. 福建省自然科学基金面上项目，2018J01657，一类受扰不确定混杂系统的极小极大最优控制，2018/04-2021/03，主持，已结题
6. 福建省自然科学基金青年项目，2014J05001，大规模不完全信息生化系统广义建模与鲁棒优化，2014/01-2017/12，主持，已结题
7. 2018年福建省高校杰出青年科研人才培育计划
已发表论文
1. Juan Wang, Chihua Chen, Jianxiong Ye*（叶剑雄）, Multi-objective optimal control of bioconversion process considering system sensitivity and control variation, Journal of Process Control, 2022, 119: 13-24.
2. 王佳，黄誉之，叶剑雄*，基于时间尺度变换的一类微生物批式流加发酵混杂切换系统的最优控制，运筹学学报，已接收，2024.
3. Jichao Wang, Xin Zhang, Jianxiong Ye（叶剑雄）*, Juan Wang, Enmin Feng, Optimizing design for continuous conversion of glycerol to 1,3-propanediol using discrete-valued optimal control, Journal of Process Control, 2021, 104: 126-134.
4. Xiaojuan Zhang, Junru Zhao, Jie Zhang, Luqiang Huang, Jianxiong Ye*（叶剑雄）, Kinetic modelling of microalgal growth and fucoxanthin synthesis in photobioreactor, International Journal of Chemical Reactor Engineering, 20(7): 723-734.
5. Juan Wang, Honglei Xu, Kok Lay Teo, Jie Sun, Jianxiong Ye*（叶剑雄）, Jichao Wang, Mixed-integer minimax dynamic optimization for structure identification of glycerol metabolic network, Applied Mathematical Modeling, 2020, 82:508-520.
6. Jinlong Yuan, Changzhi Wu, Jianxiong Ye（叶剑雄）, Jun Xie, Robust identification of nonlinear state-dependent impulsive switched system with switching duration constrains, Nonlinear Analysis: Hybrid Systems, 2020, 36: 100879.
7. Jianxiong Ye（叶剑雄）, An Li*, Necessary optimality conditions for nonautonomous optimal control problems and its applications to bilevel optimal control, Journal of Industrial and Management Optimization, 2019, 15(3): 1399-1419.
8. Jianxiong Ye（叶剑雄）, Yuxian Chen, Guanxuan Peng, Xinwei Yang, Jianzhong Huang, Chongrong Ke*, Antibacterial activity of phenyllactic acid against Staphylococcus epidermidis and its microbial production: modelling and optimization-based analysis, International Journal of Chemical Reactor Engineering, 2019, 18(1): 20190106.
9. Kobamelo Mashaba, Honglei Xu, Jianxiong Ye（叶剑雄）, Stabilization of complex manufacturing systems with state impulsiveness by hybrid sliding mode control, Dynamics of Continuous, Discrete and Impulsive Systems, Series B: Applications and Algorithms, 2019, 26: 291-302.
10. Jianxiong Ye（叶剑雄）, An Li*, Jingang Zhai, A measure of concentration robustness in a biochemical reaction network and its application on system identification. Applied Mathematical Modelling, 2018, 58: 270-280.
11. Jianxiong Ye（叶剑雄）, Honglei Xu*, Enmin Feng, Zhilong Xiu, Optimization of a fed-batch bioreactor for 1,3-propanediol production using hybrid nonlinear optimal control, Journal of Process Control, 2014, 24: 1556-1569.
12. Jingang Zhai，Teng Niu, Jianxiong Ye（叶剑雄）, Enmin Feng, Optimal control of nonlinear switched system with mixed constraints and its parallel optimization algorithm. Nonlinear Analysis: Hybrid Systems, 2017, 25: 21-40.
13. Jinlong Yuan, Yuduo Zhang, Jianxiong Ye（叶剑雄）. et al. Robust parameter identification using parallel global optimization for a batch nonlinear enzyme-catalytic time-delayed process presenting metabolic discontinuities, Applied Mathematical Modelling, 2017, 46: 554-571.
14. Jianxiong Ye（叶剑雄）, An Li, A measure of biological robustness in microbial metabolic systems and its approximated estimation. The 36th Chinese Control Conference, 2017, Dalian.
15. 柯崇榕，钟璐芳，叶剑雄，杨威，邵庆伟，黄建忠, 类球红细菌分批发酵生产辅酶Q10的动力学模型, 生物数学学报, 31(1):65-70, 2016.
16. Jianxiong Ye（叶剑雄）, Honglei Xu, Xueying Huang*, Chongrong Ke, Enmin Feng, Dynamics analysis and prediction of genetic regulation in glycerol metabolic network via structural kinetic modeling, Volume 2015, Article ID 673120.
17. Juan Wang*, Jianxiong Ye（叶剑雄）, Lei Wang, Suqin Liu, Enmin Feng, Modelling of a nonlinear switching system in microbial continuous culture and its parameter optimization via sensitivity functions, Applied Mathematical Modelling, 2015, 39: 2036-2047.
18. Chi Zhu, Genfan Liu*, Jianxiong Ye（叶剑雄）, Honglei Xu, Experimental investigation of non-stationary motion of single small spherical particles in an upward flow with different velocities, Powder Technology, 2015, 273: 111-117.
19. Jingang Zhai, Guangmao Jiang, Jianxiong Ye*（叶剑雄）, Optimal dilution strategy for a microbial continuous culture based on the biological robustness, Numerical Algebra, Control and Optimization, 2015, 5(1): 59-69.
20. Shiyun Wang*, Jianxiong Ye（叶剑雄）, Existence of bounded positive solution of a new nonlinear dynamical system in microbial continuous culture, ICIC Express Letters, 2015, 9(9): 2459-2466.
21. Shan Jiang, Lei Wang*, Jianxiong Ye（叶剑雄）, Enmin Feng, Zhilong Xiu, Optimal design of automatic control system for the fed-batch production of 1,3-propanediol with pH logic control, Systems Science & Control Engineering: An Open Access Journal, 2014, 2, 228-235.
22. Jianxiong Ye（叶剑雄）, Honglei Xu, Regularity and directional differentiability with respect to parameters of solutions to nonlinear switching systems, Proceeding of the 11th World Congress on Intelligent Control and Automation Shenyang, China, 2014, 6.29 -7.4.
23. Hongli Wang, Jianxiong Ye*（叶剑雄）, Enmin Feng, and Peiyi Li, Identification Model and Properties of the Membrane Transport Mechanism of the Microbial Enzyme Catalysis of 1,3-Propanediol Based on Robustness Analysis, Proceeding of the 11th World Congress on Intelligent Control and Automation Shenyang, China, 2014, 6.29 -7.4.
24. Jianxiong Ye*（叶剑雄）, Yuduo Zhang, Enmin Feng, Zhilong Xiu, Hongchao Yin, Nonlinear hybrid system and parameter identification of microbial fed-batch culture with open loop glycerol input and pH logic control, Applied Mathematical Modelling, 2012, 36: 357-369.
25. Juan Wang*, Jianxiong Ye（叶剑雄）, Enmin Feng, Zhilong Xiu, Modeling and parameter estimation of a nonlinear switching system in fed-batch culture with pH feedback, Applied Mathematical Modelling, 2012, 36: 4887-4897.
26. Juan Wang*, Jianxiong Ye（叶剑雄）, Hongchao Yin, Enmin Feng, Lei Wang, Sensitivity analysis and identification of kinetic parameters in batch fermentation of glycerol, Journal of Computational and Applied Mathematics，2012, 236: 2268-2276.
27. Yaqin Sun, Jianxiong Ye（叶剑雄）, Xiaojia Mu, Hu Teng, Enmin Feng, Anping Zeng, Zhilong Xiu*, Nonlinear mathematical simulation and analysis of dha regulon for glycerol metabolism in Klebsiella pneumonia, Chinese Journal of Chemical Engineering, 20(5) , 958-970, 2012.
28. Haihua Yan*, Xu Zhang, Jianxiong Ye（叶剑雄）, Enmin Feng, Identification and robustness analysis of nonlinear hybrid dynamical system concerning glycerol transport mechanism, Computers and Chemical Engineering, 2012,40: 171-180.
29. Bangyu Shen*, Chongyang Liu, Jianxiong Ye（叶剑雄）, Enmin,Feng, Zhilong Xiu, Parameter identification and optimization algorithm in microbial continuous culture, Applied Mathematical Modelling, 36(2), 585-595，2012.
30. Zhaoyi Huo, Liang Zhao, Hongchao Yin*, Jianxiong Ye（叶剑雄）, A hybrid optimization strategy for simultaneous synthesis of heat exchanger network, Korean Journal of Chemical Engineering, 29(10), 1298-1309, 2012.
31. Jianxiong Ye∗（叶剑雄）, Enmin Feng, Hongchao Yin, Zhilong Xiu, Modelling and well-posedness of a nonlinear hybrid system in fed-batch production of 1,3-propanediol with open loop glycerol input and pH logic control, Nonlinear Analysis: Real World Applications, 2011, 12: 364-376.
32. Jingang Zhai*, Jianxiong Ye（叶剑雄）, Lei Wang, Enmin Feng, Hongchao Yin, Zhilong Xiu, Pathway identification using parallel optimization for a complex metabolic system in microbial continuous culture, Nonlinear Analysis: Real World Applications, 12(5), 2730-2741, 2011.
33. Juan Wang*, Jianxiong Ye（叶剑雄）, Enmin Feng, Hongchao Yin, Zhilong Xiu, Modelling and identification of a nonlinear hybrid dynamical system in batch fermentation of glycerol, Mathematical and Computer Modelling, 54(1-2), 618-624, 2011.
34. Juan Wang*, Jianxiong Ye（叶剑雄）, Enmin Feng, Hongchao Yin, Bin Tan, Complex metabolic network of glycerol by Klebsiella pneumoniae and its system identification via biological robustness, Nonlinear Analysis: Hybrid Systems, 5(1), 102-112, 2011.
35. An Li*, Wei Lv, Jianxiong Ye（叶剑雄）, Exponential and global stability of nonlinear dynamical systems relative to initial time difference, Applied Mathematics and Computation, 2011, 217(12):5923-5929.
36. 王红丽，叶剑雄，冯恩民, 甘油生物歧化非线性平衡点及其稳定性分析, 生物数学学报, 26(2): 339-346, 2011.
37. 王诗云，杨淑辉，叶剑雄，冯恩民, 微生物连续发酵模型及其正解的存在性和稳定性分析, 生物数学学报, 25(1): 113-121, 2010.
38. Jiang Shan*, Jianxiong Ye（叶剑雄）, Enmin Feng, Zhilong Xiu, Automatic control design for optimal strategy in fed-batch culture with coupled feed of glycerol and alkali, International Journal of Chemical Reactor Engineering, A148, 2010.
39. Jianxiong Ye*（叶剑雄）, Enmin Feng, Hansheng Lian, Zhilong Xiu, Existence of equilibrium points and stability of the nonlinear dynamical system in microbial continuous cultures, Applied Mathematics and Computation, 2009, 207: 307-318.
40. Jianxiong Ye（叶剑雄）, Enmin Feng, Lei Wang, Zhilong Xiu, and Yaqin Sun, Modeling and Robustness Analysis of Biochemical Networks of Glycerol Metabolism by Klebsiella Pneumoniae, Complex 2009, Part I, LNICST 4, pp. 446-457, 2009.